Role of Marek's Disease Virus (MDV)-Encoded U S 3 Serine/Threonine Protein Kinase in Regulating MDV Meq and Cellular CREB Phosphorylation

Marek's disease (MD) is a neoplastic disease of chickens caused by Marek's disease virus (MDV), a member of the subfamily Like other alphaherpesviruses, MDV encodes a serine/threonine protein kinase, U 3. The functions of U 3 have been extensively studied in other alphaherpesviruses; howev...

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Veröffentlicht in:	Journal of virology 2020-08, Vol.94 (17)
Hauptverfasser:	Liao, Yifei, Lupiani, Blanca, Bajwa, Kanika, Khan, Owais A, Izumiya, Yoshihiro, Reddy, Sanjay M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alphaherpesvirinae - genetics Animals Cell Line Cell Transformation, Viral - genetics Chickens - virology Chromatin Immunoprecipitation Gene Dosage Gene Expression Regulation, Viral HEK293 Cells Herpesvirus 2, Gallid - enzymology Herpesvirus 2, Gallid - genetics Humans Marek Disease - virology Phosphorylation Poultry Promoter Regions, Genetic Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Signal Transduction Transfection Viral Proteins - genetics Viral Proteins - metabolism
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