Catalase-Negative Staphylococcus aureus Strain with Point Mutations in the katA Gene

Methicillin-susceptible catalase-negative Staphylococcus aureus strain UCN61 was isolated from an arterial leg ulcer. The deduced sequence of the structural katA gene for the catalase was 99% identical to those of other S. aureus strains. Two mutations were identified in katA from S. aureus UCN61, i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Clinical Microbiology 2008-06, Vol.46 (6), p.2060-2061
Hauptverfasser:	Piau, C, Jehan, J, Leclercq, R, Daurel, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arterial Occlusive Diseases - complications Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Catalase - genetics Catalase - metabolism Female Fundamental and applied biological sciences. Psychology Humans Leg Ulcer - diagnosis Leg Ulcer - microbiology Microbiology Miscellaneous Point Mutation Staphylococcal Infections - diagnosis Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - enzymology Staphylococcus aureus - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Methicillin-susceptible catalase-negative Staphylococcus aureus strain UCN61 was isolated from an arterial leg ulcer. The deduced sequence of the structural katA gene for the catalase was 99% identical to those of other S. aureus strains. Two mutations were identified in katA from S. aureus UCN61, including one leading to a substitution of key histidine 58 by a tyrosine.
ISSN:	0095-1137 1098-660X 1098-5530
DOI:	10.1128/JCM.02300-07