Comparison of Cefoxitin and Oxacillin Disk Diffusion Methods for Detection of mecA-Mediated Resistance in Staphylococcus aureus in a Large-Scale Study

The recommended breakpoints for the cefoxitin disk diffusion test for Staphylococcus aureus were recently modified. In this large-sample study, cefoxitin sensitivity and specificity compared to those of oxacillin were 97.3% and 100%, respectively. This study validated the new cefoxitin breakpoints f...

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Veröffentlicht in:	Journal of Clinical Microbiology 2009-01, Vol.47 (1), p.217-219
Hauptverfasser:	Broekema, Nicole M, Van, Tam T, Monson, Timothy A, Marshall, Steven A, Warshauer, David M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteriology Cefoxitin - pharmacology Humans Methicillin-Resistant Staphylococcus aureus - drug effects Microbial Sensitivity Tests Oxacillin - pharmacology Sensitivity and Specificity Staphylococcal Infections - microbiology Staphylococcus aureus
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Zusammenfassung:	The recommended breakpoints for the cefoxitin disk diffusion test for Staphylococcus aureus were recently modified. In this large-sample study, cefoxitin sensitivity and specificity compared to those of oxacillin were 97.3% and 100%, respectively. This study validated the new cefoxitin breakpoints for the detection of mecA-mediated resistance in S. aureus.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.01506-08