Genome Sequence of Mycobacterium hassiacum DSM 44199, a Rare Source of Heat-Stable Mycobacterial Proteins

Mycobacterium hassiacum is a rapidly growing mycobacterium isolated from human urine and so far the most thermophilic among mycobacterial species. Its thermotolerance and phylogenetic relationship to M. tuberculosis render its proteins attractive tools for crystallization and structure-guided drug d...

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Veröffentlicht in:	Journal of Bacteriology 2012-12, Vol.194 (24), p.7010-7011
Hauptverfasser:	Tiago, Igor, Maranha, Ana, Mendes, Vitor, Alarico, Susana, Moynihan, Patrick J, Clarke, Anthony J, Macedo-Ribeiro, Sandra, Pereira, Pedro J. B, Empadinhas, Nuno
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial proteins Bacterial Proteins - metabolism Bacteriology Base Composition Base Sequence Biological and medical sciences crystallization DNA, Bacterial - genetics drugs Fundamental and applied biological sciences. Psychology genome Genome Announcements Genome, Bacterial Genomes Gram-positive bacteria heat stability heat tolerance Hot Temperature Humans Microbiology Miscellaneous Molecular Sequence Data Mycobacterium hassiacum Mycobacterium tuberculosis Nontuberculous Mycobacteria - classification Nontuberculous Mycobacteria - genetics Nontuberculous Mycobacteria - isolation & purification nucleotide sequences Pharmaceuticals Phylogenetics Phylogeny Protein Stability proteins RNA, Bacterial - genetics Sequence Analysis, DNA urine Urine - microbiology
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Beschreibung
Zusammenfassung:	Mycobacterium hassiacum is a rapidly growing mycobacterium isolated from human urine and so far the most thermophilic among mycobacterial species. Its thermotolerance and phylogenetic relationship to M. tuberculosis render its proteins attractive tools for crystallization and structure-guided drug design. We report the draft genome sequence of M. hassiacum DSM 44199.
ISSN:	0021-9193 1098-5530 1067-8832
DOI:	10.1128/JB.01880-12