Central Nervous System Dysfunction Due to Lead Exposure

Central Nervous System Dysfunction Due to Lead Exposure

Central nervous system dysfunction was investigated in workers at a secondary lead smelter by means of performance tests. Correlations between test scores and zinc protoporphyrin levels, a biological indicator of lead toxicity, are statistically significant. This correlation should prove to be usefu...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1978-08, Vol.201 (4354), p.465-467
Hauptverfasser: Valciukas, José A., Lilis, Ruth, Fischbein, Alf, Selikoff, I. J., Eisinger, Josef, Blumberg, William E.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Behavior - physiology
Blood
Central nervous system
Central Nervous System - physiopathology
Cultured cells
Environmental Exposure
Humans
Lead
Lead - blood
Lead Poisoning - blood
Lead Poisoning - physiopathology
Middle Aged
Neurologic Examination - methods
Neurons
Occupational Diseases - physiopathology
Opioid analgesics
Performance tests
Porphyrins - blood
Protoporphyrins - blood
Smelters
Spinal cord
Zinc
Zinc - blood
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Beschreibung
Zusammenfassung:Central nervous system dysfunction was investigated in workers at a secondary lead smelter by means of performance tests. Correlations between test scores and zinc protoporphyrin levels, a biological indicator of lead toxicity, are statistically significant. This correlation should prove to be useful in current efforts to evaluate effects of lead exposure.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.663669