Semliki Forest Virus: Cause of a Fatal Case of Human Encephalitis

A fatal case of human encephalitis has been observed for which our results indicate that Semliki Forest virus (SFV) was the etiologic agent. This is surprising in view of the fact that this virus, which has been widely studied, was believed to be one of the arboviruses nonpathogenic for man. Describ...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1979-03, Vol.203 (4385), p.1127-1129
Hauptverfasser:	Willems, W. R., Kaluza, G., Boschek, C. B., Bauer, H., Hager, H., H.-J. Schütz, Feistner, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Antigens Antigens, Viral - analysis Antiserum Arbovirus Infections - etiology Arboviruses Ascitic Fluid Encephalitis - etiology Encephalitis - microbiology Encephalitis - pathology Female Gels Humans Infections Laboratory Infection - etiology Laboratory Infection - microbiology Mice Semliki forest virus Semliki forest virus - immunology Viruses
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Beschreibung
Zusammenfassung:	A fatal case of human encephalitis has been observed for which our results indicate that Semliki Forest virus (SFV) was the etiologic agent. This is surprising in view of the fact that this virus, which has been widely studied, was believed to be one of the arboviruses nonpathogenic for man. Described are the clinical course, the virological examinations performed, and the histopathological findings in the central nervous system.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.424742