Transcription Factor II: A Structure with Multiple Functions

The process of transcription, by which RNA is read from DNA, is executed by a large complex of 40 to 50 proteins. The crystal structure of three molecules at the core of this complex is presented by Geiger et al. ( p. 830 ) in this issue of Science . In their Perspective, Jacobson and Tjian explain...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1996-05, Vol.272 (5263), p.827-828
Hauptverfasser: Jacobson, Raymond H., Tjian, Robert
Format: Artikel
Sprache:eng
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Zusammenfassung:The process of transcription, by which RNA is read from DNA, is executed by a large complex of 40 to 50 proteins. The crystal structure of three molecules at the core of this complex is presented by Geiger et al. ( p. 830 ) in this issue of Science . In their Perspective, Jacobson and Tjian explain why the resolution of this structure is an important step on the road to understanding the entire transcription machinery.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.272.5263.827