Radiation Leukemia Virus: Quantitative Tissue Culture Assay

Radiation leukemia virus does not propagate in tissue cultures from either Swiss or C57BL mouse embryos, but it does augment focus formation by the defective Moloney leukemia pseudotype of murine sarcoma virus in Swiss mouse cells and thus an be quantitatively assayed.

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Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1969-07, Vol.165 (3890), p.306-309
Hauptverfasser:	Fischinger, Peter J., O'Connor, Timothy E.
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL CELLS Animals Cell culture techniques CELL CULTURES CELLS, CULTURED/radioinduced leukemia in fibroblast, from C57BL/6 mice, role of virus induction in x Culture Techniques Cultured cells DISEASES, NEOPLASTIC/leukemia, radioinduced, in cultured fibroblast cells, role of virus induction in x Embryonic cells Embryos Fibroblasts Helper Viruses IN VITRO Infections LEUKEMIA Leukemia Virus, Murine Leukemia, Radiation-Induced - microbiology MICE Moloney murine leukemia virus Murine leukemia virus N28600 -Life Sciences-Radiation Effects on Animals PRODUCTION RADIATION INJURIES SOLUTIONS Swiss 3T3 cells Virus Cultivation VIRUSES VIRUSES/Rad LV, assay in cells of Swiss mice, quantitative X RADIATION X RADIATION/effects on fibroblast cells from Swiss mice, isolation of Rad LW-MSV virus following leukemogenic
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Beschreibung
Zusammenfassung:	Radiation leukemia virus does not propagate in tissue cultures from either Swiss or C57BL mouse embryos, but it does augment focus formation by the defective Moloney leukemia pseudotype of murine sarcoma virus in Swiss mouse cells and thus an be quantitatively assayed.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.165.3890.306