Tumor-Specific Antigens Detected by Inhibition of Macrophage Migration

Tumor-Specific Antigens Detected by Inhibition of Macrophage Migration

Tumor-specific antigens of a guinea pig hepatoma induced by diethylnitrosamine were detected by the inhibition of migration of specifically sensitized macrophages from capillary tubes, and by the local passive transfer of delayed skin hypersensitivity and the suppression of growth of intradermally i...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1969-07, Vol.165 (3890), p.296-297
Hauptverfasser: Kronman, Barry S., Wepsic, Harold T., Churchill, Winthrop H., Zbar, Berton, Borsos, Tibor, Rapp, Herbert J.
Format: Artikel
Sprache:eng
Schlagworte:
Animal migration behavior
Animals
Antigens
Antigens - analysis
Capillary tubes
Carcinoma, Hepatocellular - chemically induced
Carcinoma, Hepatocellular - immunology
Cell growth
Cell lines
Delayed hypersensitivity
Guinea Pigs
Hepatocellular carcinoma
Hypersensitivity, Delayed
Immunity, Maternally-Acquired
Liver Neoplasms
Macrophages
Macrophages - immunology
Methods
Neoplasm Transplantation
Nitrosamines
Skin Tests
Transplantation Immunology
Tumors
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Zusammenfassung:Tumor-specific antigens of a guinea pig hepatoma induced by diethylnitrosamine were detected by the inhibition of migration of specifically sensitized macrophages from capillary tubes, and by the local passive transfer of delayed skin hypersensitivity and the suppression of growth of intradermally injected tumor.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.165.3890.296