Corneal Calcification

Superficial calcification was produced in the normal rabbit cornea by mild irradiation with a carbon dioxide laser. The calcification was entirely extracellular and closely resembled that observed in human band keratopathy, which was characterized as hydroxyapatite by x-ray diffraction. The electron...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1968-10, Vol.162 (3849), p.129-130
Hauptverfasser:	Fine, Ben S., Berkow, Joseph W., Fine, Samuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcinosis Calcinosis - etiology Calcinosis - pathology Carbon Dioxide Cell membranes Cornea Cornea - pathology Cornea - radiation effects Corneal Opacity - etiology Crystals Epithelial cells Epithelium Hydroxyapatites - analysis Irradiation Lasers - adverse effects Microscopy, Electron Pathology Rabbits Radiation Injuries, Experimental - pathology X-Ray Diffraction
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Beschreibung
Zusammenfassung:	Superficial calcification was produced in the normal rabbit cornea by mild irradiation with a carbon dioxide laser. The calcification was entirely extracellular and closely resembled that observed in human band keratopathy, which was characterized as hydroxyapatite by x-ray diffraction. The electron-microscopic appearance of calcific spherules and conglomerates in early corneal calcification is presented. The calcific spherules arise at the basal plasma membrane surface of the epithelial cells in close relation to their basement membrane.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.162.3849.129