Audiogenic Seizures, the Dilute Locus, and Phenylalanine Hydroxylase in DBA/1 Mice

Audiogenic Seizures, the Dilute Locus, and Phenylalanine Hydroxylase in DBA/1 Mice

Reduced audiogenic seizure susceptibility in dilute mice was associated with enhancement of phenylalanine hydroxylase activity, previously reported as low in dilute mice. Though nutritional changes complicate the interpretation, evidence exists for a mutation linked with dilute which modifies suscep...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1964-04, Vol.144 (3616), p.304-305
Hauptverfasser: Huff, Sally D., Fuller, John L.
Format: Artikel
Sprache:eng
Schlagworte:
Alleles
Audiogenic seizures
Enzyme activity
Experimentation
Female animals
Genetic loci
Genotypes
Insect eggs
Mice
Seizures
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Zusammenfassung:Reduced audiogenic seizure susceptibility in dilute mice was associated with enhancement of phenylalanine hydroxylase activity, previously reported as low in dilute mice. Though nutritional changes complicate the interpretation, evidence exists for a mutation linked with dilute which modifies susceptibility.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.144.3616.304