Deoxycytidine in Urine of Humans after Whole-Body Irradiation

Deoxycytidine in Urine of Humans after Whole-Body Irradiation

Increased levels of deoxycytidine were found in the urine of two humans during the first 24 hours after irradiation. This substance presumably was produced by the breakdown of DNA following irradiation, or resulted from interference with the synthesis of DNA.

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Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1963-10, Vol.142 (3590), p.396-398
Hauptverfasser: Berry, Helen K., Saenger, Eugene L., Perry, Harold, Friedman, Ben I., Kereiakes, James G., Scheel, Carolyn
Format: Artikel
Sprache:eng
Schlagworte:
BIOCHEMISTRY
BIOLOGY AND MEDICINE
BODY
Brain
Catecholamines
CYTIDINE
DEOXYCYTIDINE
DNA
Excretion
Fetus
Gels
Hemoglobins
Humans
Inbred strains
IRRADIATION
MAN
METABOLISM
NUCLEIC ACIDS
Nucleosides
QUALITATIVE ANALYSIS
Radiation Effects
RADIATION SICKNESS
REACTION KINETICS
URINE
Whole body irradiation
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Beschreibung
Zusammenfassung:Increased levels of deoxycytidine were found in the urine of two humans during the first 24 hours after irradiation. This substance presumably was produced by the breakdown of DNA following irradiation, or resulted from interference with the synthesis of DNA.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.142.3590.396