A novel HLA‐B variant, HLA‐B14:02:16, discovered by amplicon‐based next‐generation sequencing

A novel HLA‐B variant, HLA‐B14:02:16, discovered by amplicon‐based next‐generation sequencing

HLA‐B*14:02:16 differs from B*14:02:01:01 by a synonymous nucleotide substitution in codon 141.

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Bibliographische Detailangaben
Veröffentlicht in:HLA 2018-11, Vol.92 (5), p.323-324
Hauptverfasser: Balz, Vera, Fischer, Johannes, Krause, Stefan, Enczmann, Juergen
Format: Artikel
Sprache:eng
Schlagworte:
Base Sequence
Blood Donors
Codon
Genetic Variation
Genotype
Hematopoietic Stem Cell Transplantation
High-Throughput Nucleotide Sequencing - methods
Histocompatibility Testing - methods
HLA-B14 Antigen - genetics
Humans
Male
next‐generation sequencing
novel HLA‐B allele
Polymerase Chain Reaction
Sequence Analysis, DNA - methods
Sequence Homology
Silent Mutation
synonymous variation
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Beschreibung
Zusammenfassung:HLA‐B*14:02:16 differs from B*14:02:01:01 by a synonymous nucleotide substitution in codon 141.
ISSN:2059-2302
2059-2310
DOI:10.1111/tan.13384