Effects of Flunixin Meglumine and Prostaglandin F 2 α Treatments on the Development and Quality of Bovine Embryos In Vitro

Assisted reproduction procedures, such as embryo transfer ( ET ) and artificial insemination ( AI ), in cattle could induce the secretion of prostaglandin F 2 ‐alpha ( PGF 2 α ) from uterine horns which may in turn interrupt embryo development and implantation. This study investigated the effect of flunixin meglumine ( FM ), prostaglandin F2 alpha ( PGF 2 α ) and FM combined with PGF 2 α supplementation in culture medium ( IVC ‐ II ) on the development and quality of in vitro produced bovine embryos. The development rate of embryos was significantly higher in the FM group (33.3%) than in control (24.3%), PGF 2 α (23.9%) and FM + PGF 2 α groups (24.5%). The percentage of hatched blastocysts was also higher (p