Identification of 5‐(3‐(methylsulfonyl)phenyl)‐3‐(4‐(methylsulfonyl)phenyl)‐ 3 H ‐imidazo[4,5‐ b ]pyridine as novel orally bioavailable and metabolically stable antimalarial compound for further exploration

Malaria continues to be a significant public health problem threatened by the emergence and spread of resistance to artemisinin‐based combination therapies and marked half a million deaths in 2016. A new imidazopyridine chemotype has been envisaged through scaffold‐hopping approach combined with doc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical biology & drug design 2023-03, Vol.101 (3), p.690-695
Hauptverfasser: Kundu, Mrinalkanti, Dutta, Aditi, Roy, Kuldeep K., Mal, Sajal K., Karmakar, Shouvik, Mandal, Aritra, Mondal, Susanta K., Kumar, Sanjay, Saha, Soumya, Pradhan, Subhankar, Sarkar, Ratul, Chakrabarti, Monali, Malik, Pradip K., Banerjee, Manish
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!