Identification of 5‐(3‐(methylsulfonyl)phenyl)‐3‐(4‐(methylsulfonyl)phenyl)‐ 3 H ‐imidazo[4,5‐ b ]pyridine as novel orally bioavailable and metabolically stable antimalarial compound for further exploration
Malaria continues to be a significant public health problem threatened by the emergence and spread of resistance to artemisinin‐based combination therapies and marked half a million deaths in 2016. A new imidazopyridine chemotype has been envisaged through scaffold‐hopping approach combined with doc...
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Veröffentlicht in: | Chemical biology & drug design 2023-03, Vol.101 (3), p.690-695 |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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