Bioelectronic Imaging Array Based on Bacteriorhodopsin Film

A photoreceptor array that exploits the light sensitive bacteriorhodopsin (bR) films has been manufactured on a flexible indium-tin-oxide (ITO) coated plastic film using electrophoretic sedimentation technique (EPS). The effective sensing area of each photoreceptor is 2 × 2 mm 2 , separated by 1 mm...

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Veröffentlicht in:IEEE transactions on nanobioscience 2008-12, Vol.7 (4), p.249-256
Hauptverfasser: Wei Wei Wang, Knopf, G.K., Bassi, A.S.
Format: Magazinearticle
Sprache:eng
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Zusammenfassung:A photoreceptor array that exploits the light sensitive bacteriorhodopsin (bR) films has been manufactured on a flexible indium-tin-oxide (ITO) coated plastic film using electrophoretic sedimentation technique (EPS). The effective sensing area of each photoreceptor is 2 × 2 mm 2 , separated by 1 mm and arranged in a 4 × 4 array. A switched integrator with gain on the order of 10 10 is used to amplify the signal to a suitable level. When exposed to light, the differential response characteristic is attributed to charge displacement and recombination within bR molecules, as well as loading effects of the attached amplifier. The peak spectral response occurs at 568 nm and is linear over the tested light power range of 200 ¿ W to 12 mW. The response remains linear at other tested wavelengths, but with reduced amplitude. Initial tests have indicated that responsivity among all photoreceptors is greater than 71% of the average value, 465.25 mV/mW. The differential nature of the signal generated by bR makes it a suitable sensing material for vision applications such as motion detection. The prototype array demonstrates this property by employing Reichardt's delay-and-correlate algorithm. Furthermore, fabricating sensor arrays on flexible substrates introduces a new design approach that enables non-planar imaging surfaces.
ISSN:1536-1241
1558-2639
DOI:10.1109/TNB.2008.2011851