Attenuation Correction Synthesis for Hybrid PET-MR Scanners: Application to Brain Studies

Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not direc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:IEEE transactions on medical imaging 2014-12, Vol.33 (12), p.2332-2341
Hauptverfasser: Burgos, Ninon, Cardoso, M. Jorge, Thielemans, Kris, Modat, Marc, Pedemonte, Stefano, Dickson, John, Barnes, Anna, Ahmed, Rebekah, Mahoney, Colin J., Schott, Jonathan M., Duncan, John S., Atkinson, David, Arridge, Simon R., Hutton, Brian F., Ourselin, Sebastien
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.
ISSN:0278-0062
1558-254X
DOI:10.1109/TMI.2014.2340135