Simulating the Effects of Skin Thickness and Fingerprints to Highlight Problems With Non-Invasive RF Blood Glucose Sensing From Fingertips

The non-invasive measurement of blood glucose is a popular research topic where RF/microwave sensing of glucose is one of the promising methods in this area. From the many available measurement sites in the human body, fingertips appear to be a good choice due to a good amount of fresh blood supply and homogeneity in terms of biological layers present. The non-invasive RF measurement of blood glucose relies on the detection of the change in the permittivity of the blood using a resonator as a sensor. However, the change in the permittivity of blood due to the variation in glucose content has a limited range resulting in a very small shift in the sensor's frequency response. Any inconsistency between measurements may hinder the measurement results. These inconsistencies mostly arise from the varied thickness of the biological layers and variation of fingerprints that are unique to every human. Therefore, the effects of biological layers and fingerprints in fingertips were studied in detail and are reported in this paper.