Sandine: a catharanthus‐derived alkaloid

Sandine, C21H22N2O3, which is a naturally occurring biologically active product derived from plants, is important as a possible starting material for the syntheses of valuable pharmaceuticals. The sandine framework consists of two five‐ and three six‐membered condensed rings. One of the six‐membered rings adopts a screw‐boat conformation, one adopts an envelope conformation and the third is planar. Both five‐membered rings have envelope structures. Mol­ecules are linked into dimers by N—H⋯O hydrogen bonds. The asymmetric unit contains two mol­ecules.