Genomic insight into the Streptomyces aurantiacus clade: reclassification of Streptomyces ederensis as a later heterotypic synonym of Streptomyces umbrinus and Streptomyces glomeroaurantiacus as a later heterotypic synonym of Streptomyces aurantiacus

The taxonomic relationships and genome features of the type strains in the clade, including , , , , , and , were investigated. Type strains of these species shared high 16S rRNA gene sequence similarity to each other. Multilocus sequence analysis (MLSA) based on , , , and genes revealed that and belong to the same species. Also, and belong to the same species, but the remaining species are not closely related to each other. MLSA results were verified by the results average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) analyses; while the ANI and dDDH values between and are 98.1 and 85.4 %, respectively, these values between and are 98.9 and 90.7 %, respectively. The presence of almost the same set of biosynthetic gene clusters and highly consistent phenotypic test results also supported the synonymy between and , as well as between and . Therefore, should be reclassified as a later heterotypic synonym of and should be reclassified as a later heterotypic synonym of .