The Production and Characterization of Monoclonal Antibodies against the Protein III of Neisseria gonorrhoeae

Murex Medical Research, Huntingdon Road Laboratories, Cambridge CB3 ODJ, UK ABSTRACT SUMMARY: Monoclonal antibodies were produced against gonococcal protein III. Antibodies of two different specificities were obtained. One reacted with all Neisseria species tested ( N. gonorrhoeae, N. meningitidis a...

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Veröffentlicht in:	Journal of general microbiology 1988-04, Vol.134 (4), p.1005-1008
Hauptverfasser:	Copley, C. G, Macfarlane, Sandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - biosynthesis Bacterial Outer Membrane Proteins - immunology Bacteriological methods and techniques used in bacteriology Bacteriology Biological and medical sciences Fundamental and applied biological sciences. Psychology Mice Mice, Inbred BALB C Microbiology Neisseria gonorrhoeae Neisseria gonorrhoeae - immunology Neisseria meningitidis Neisseria meningitidis - immunology
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Zusammenfassung:	Murex Medical Research, Huntingdon Road Laboratories, Cambridge CB3 ODJ, UK ABSTRACT SUMMARY: Monoclonal antibodies were produced against gonococcal protein III. Antibodies of two different specificities were obtained. One reacted with all Neisseria species tested ( N. gonorrhoeae, N. meningitidis and five non-pathogenic species), whereas the other was specific for Neisseria gonorrhoeae and may provide the basis for improved diagnostic reagents. Present address: Dunn Clinical Nutrition Centre, 100 Tennis Court Road, Cambridge CB2 12L, UK. Present address: 8 Weston Grove, Fulbourn, Cambridge CB1 5DY, UK.
ISSN:	0022-1287 1350-0872 1465-2080
DOI:	10.1099/00221287-134-4-1005