Nitrofurantoin-Induced Systemic Inflammatory Response Syndrome

Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent i...

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Veröffentlicht in:	The American journal of the medical sciences 2009-10, Vol.338 (4), p.338-340
Hauptverfasser:	Forster, Christopher J., Cohee, Brian M., Wood-Morris, Robert N., Hartzell, Joshua D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse drug reaction Aged Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Escherichia coli Infections - complications Escherichia coli Infections - drug therapy Fever General aspects Gram-Negative Bacterial Infections - drug therapy Gram-Negative Bacterial Infections - microbiology Humans Leukocytosis Male Medical sciences Nitrofurantoin Nitrofurantoin - adverse effects Nitrofurantoin - therapeutic use Pharmacology. Drug treatments Stenotrophomonas - isolation & purification Systemic inflammatory response syndrome Systemic Inflammatory Response Syndrome - chemically induced Systemic Inflammatory Response Syndrome - complications Urinary Bladder Neoplasms - complications Urinary Bladder Neoplasms - drug therapy
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Zusammenfassung:	Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent infection.
ISSN:	0002-9629 1538-2990
DOI:	10.1097/MAJ.0b013e3181abd9f6