Intensity-modulated radiotherapy with simultaneous integrated boost to dominant intraprostatic lesion: preliminary report on toxicity

To evaluate the feasibility of intensity-modulated radiotherapy with simultaneous integrated boost to the dominant intraprostatic lesion for definitive treatment of prostate cancer. Patients were deemed eligible for the study if they had histologically proven stage cT2-T3 N0M0 prostate adenocarcinom...

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Veröffentlicht in:	American journal of clinical oncology 2012-04, Vol.35 (2), p.158-162
Hauptverfasser:	Ippolito, Edy, Mantini, Giovanna, Morganti, Alessio G, Mazzeo, Ercole, Padula, Gilbert D A, Digesù, Cinzia, Cilla, Savino, Frascino, Vincenzo, Luzi, Stefano, Massaccesi, Mariangela, Macchia, Gabriella, Deodato, Francesco, Mattiucci, Gian Carlo, Piermattei, Angelo, Cellini, Numa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adenocarcinoma - radiotherapy Aged Aged, 80 and over Androgen Antagonists - therapeutic use Antineoplastic Agents, Hormonal - therapeutic use Dose Fractionation Feasibility Studies Follow-Up Studies Humans Kaplan-Meier Estimate Magnetic Resonance Imaging Male Middle Aged Neoadjuvant Therapy - methods Neoplasm Staging Prospective Studies Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Prostatic Neoplasms - radiotherapy Radiotherapy, Intensity-Modulated - adverse effects Radiotherapy, Intensity-Modulated - methods Treatment Outcome
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Beschreibung
Zusammenfassung:	To evaluate the feasibility of intensity-modulated radiotherapy with simultaneous integrated boost to the dominant intraprostatic lesion for definitive treatment of prostate cancer. Patients were deemed eligible for the study if they had histologically proven stage cT2-T3 N0M0 prostate adenocarcinoma. In addition
ISSN:	0277-3732 1537-453X
DOI:	10.1097/COC.0b013e318209cd8f