Audit of cyclosporin use in inflammatory bowel disease: limited benefits, numerous side-effects

BACKGROUND AIM PATIENTS AND METHODS RESULTS CONCLUSIONAlthough the initial response rates are encouraging, the long-term results are poor and at the expense of a high incidence of side-effects. We feel that the use of cyclosporin in IBD should be reconsidered until more information from randomized c...

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Veröffentlicht in:	European journal of gastroenterology & hepatology 2000-06, Vol.12 (6), p.657-660
Hauptverfasser:	Haslam, Neil, Hearing, Stephen D, Probert, Christopher S. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cyclosporine - adverse effects Cyclosporine - therapeutic use Digestive system Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Inflammatory Bowel Diseases - drug therapy Medical sciences Middle Aged Pharmacology. Drug treatments Retrospective Studies
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Zusammenfassung:	BACKGROUND AIM PATIENTS AND METHODS RESULTS CONCLUSIONAlthough the initial response rates are encouraging, the long-term results are poor and at the expense of a high incidence of side-effects. We feel that the use of cyclosporin in IBD should be reconsidered until more information from randomized controlled studies becomes available. Eur J Gastroenterol Hepatol 12:657-660
ISSN:	0954-691X 1473-5687
DOI:	10.1097/00042737-200012060-00015