Bleeding tendency possibly related to increased plasma antithrombin III activity in patient treated with piroxicam

A patient with chronic rheumatoid arthritis under treatment with steroids was given piroxicam (Feldene) for relief of pain and disability. Overt cutaneous and occult gastrointestinal bleeding developed after two months of treatment. Bleeding subsided and laboratory values returned to normal upon dis...

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Veröffentlicht in:	Southern medical journal (Birmingham, Ala.) Ala.), 1984-05, Vol.77 (5), p.633-634
Hauptverfasser:	Stefanini, M, Claustro, L Z, Mulkey, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antithrombin III - analysis Arthritis, Rheumatoid - drug therapy Bleeding Time Chronic Disease Ecchymosis - chemically induced Female Gastrointestinal Hemorrhage - chemically induced Humans Piroxicam Thiazines - adverse effects
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Beschreibung
Zusammenfassung:	A patient with chronic rheumatoid arthritis under treatment with steroids was given piroxicam (Feldene) for relief of pain and disability. Overt cutaneous and occult gastrointestinal bleeding developed after two months of treatment. Bleeding subsided and laboratory values returned to normal upon discontinuation of the drug.
ISSN:	0038-4348
DOI:	10.1097/00007611-198405000-00023