Paroxetine and pindolol: a randomized trial of serotonergic autoreceptor blockade in the reduction of antidepressant latency

A double-blind, randomized, placebo-controlled, parallel group study was performed in 80 adult outpatients meeting ICD-10 criteria for major depression and with a Montgomery -Asberg Depression Rating Scale (MADRS) score of at least 18 at baseline. All patients received paroxetine (20 mg once a day)...

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Veröffentlicht in:	International clinical psychopharmacology 1997-03, Vol.12 (2), p.81-90
Hauptverfasser:	Tome, M B, Isaac, M T, Harte, R, Holland, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - administration & dosage Adrenergic beta-Antagonists - adverse effects Adult Aged Biological and medical sciences Depressive Disorder - diagnosis Depressive Disorder - drug therapy Depressive Disorder - psychology Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Drug Synergism Drug Therapy, Combination Female Humans Male Medical sciences Middle Aged Neuropharmacology Paroxetine - administration & dosage Paroxetine - adverse effects Pharmacology. Drug treatments Pindolol - administration & dosage Pindolol - adverse effects Psychiatric Status Rating Scales Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Serotonin Uptake Inhibitors - administration & dosage Serotonin Uptake Inhibitors - adverse effects
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