Olsalazine as an Alternative Therapy in a Patient with Sulfasalazine-Induced Eosinophilic Pneumonia

A man with Crohnʼs colitis developed eosinophilic pneumonia after treatment with sulfasalazine. Challenge with sulfapyridine revealed that this component of sulfasalazine was the likely causative agent. Treatment with olsalazine, a 5-aminosalicylic acid compound (disodium-azodisalicylate), was well...

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Veröffentlicht in:Journal of clinical gastroenterology 1988-04, Vol.10 (2), p.218-220
Hauptverfasser: Scherpenisse, J, van der Valk, P D. L. P. M, van den Bosch, J M. M, van Hees, P A. M, Nadorp, J H. S. M
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Sprache:eng
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Zusammenfassung:A man with Crohnʼs colitis developed eosinophilic pneumonia after treatment with sulfasalazine. Challenge with sulfapyridine revealed that this component of sulfasalazine was the likely causative agent. Treatment with olsalazine, a 5-aminosalicylic acid compound (disodium-azodisalicylate), was well tolerated without recurrence of pulmonary symptoms.
ISSN:0192-0790
1539-2031
DOI:10.1097/00004836-198804000-00024