Clomipramine-induced Tourettism in obsessive-compulsive disorder : clinical and theoretical implications

We report a case in which vocal and motor tics (Tourettism) developed after the administration of clomipramine hydrochloride in a young patient with obsessive compulsive disorder and schizoid personality disorder. Several hypotheses for this occurrence are proposed based on the suggested pathogenesi...

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Veröffentlicht in:	Clinical neuropharmacology 1994-08, Vol.17 (4), p.338-343
Hauptverfasser:	MOSHE, K, IULIAN, I, SETH, K, ELI, L, JOSEPH, Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antidepressive Agents, Tricyclic - adverse effects Antidepressive Agents, Tricyclic - therapeutic use Biological and medical sciences Clomipramine - adverse effects Clomipramine - therapeutic use Drug toxicity and drugs side effects treatment Humans Male Medical sciences Obsessive-Compulsive Disorder - drug therapy Pharmacology. Drug treatments Tourette Syndrome - chemically induced Toxicity: nervous system and muscle
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Beschreibung
Zusammenfassung:	We report a case in which vocal and motor tics (Tourettism) developed after the administration of clomipramine hydrochloride in a young patient with obsessive compulsive disorder and schizoid personality disorder. Several hypotheses for this occurrence are proposed based on the suggested pathogenesis of Tourette syndrome.
ISSN:	0362-5664 1537-162X
DOI:	10.1097/00002826-199408000-00005