An overview of the relationship between alkylating agents and therapy-related acute nonlymphocytic leukemia

Patients with therapy-related acute nonlymphocytic leukemia present many challenges to health care professionals, yet it is only through the success of cancer management that we have uncovered this rare and unfortunate issue of survivorship. Oncology nurses have been at the forefront of symptom management, pain management, and other important issues in the care of cancer patients, and with a broader under-standing can also emerge as key players in the identification and management of patients with second malignancies.