40 Arthralgia and celiac disease

Abstract Background In a large cohort of 2125 children followed in rheumatology, 2% had celiac disease (CD) (about 3 times the rate in the general population). Inversely, CD was reported in up to 2–3% of children with juvenile idiopathic arthritis Objectives Reporting joint damage such as arthrlagia in a celiac pediatric cohort Material and method We collected 58 celiac children and reported those with arthralgia and studied their clinical aspects Results Arthralgia was reported in 10/58 children (i.e. 17.24%) of the entire cohort studied (n = 58), including 09 children with positive HLA DQ2/DQ8 typing, potentially with an autoimmune background. The arthralgia was not accompanied by arthritis, and had an apyretic, labile and transient character. Only one case of episodic spinal pain was reported in the history Conclusion More than a sixth of the pediatric celiac cohort presents with arthralgia. These joint pains can be caused by vitamin D deficiency, osteoporosis, associated juvenile idiopathic arthritis (JIA), in particular HIV-positive. They can also be isolated and respond to the gluten-free diet.