Efficacy of Nasal Steroid Irrigation in Chronic Rhinosinusitis after Sinus Surgery: A Meta-Analysis Study

Abstract Background Chronic rhinosinusitis (CRS) is a frequent multifactorial inflammatory disorder that ranges from single sinus disease to extensive sinonasal airway inflammation that reduces the patient's quality of life. The goal of CRS treatment is to decrease infectious exacerbations while controlling inflammation. Methods We conducted a meta-analysis study to assess the efficacy of nasal steroid irrigation in CRS after sinus surgery. This study included published medical articles from 1990 till 2023 concerning the efficacy of nasal steroid irrigation in CRS after sinus surgery through the Medline data base (PubMed), Web of science, Springer, Cochrane library, EMBASE. Results Sixteen studies (n = 678) met the inclusion criteria and were reviewed and analyzed. Nasal steroid irrigation resulted in statistically highly significant improvement (p