Impact of Coronary Revascularization on Left Ventricular Global Longitudinal Strain in Chronic Total Occlusion

Abstract Background Ischemia is the cause of decreased ventricular relaxation and diastolic dysfunction, which is followed by reduced systolic function. This sequence of events is the outcome of a chain reaction that starts with metabolic and biochemical changes. A temporary impairment in ventricular relaxation is brought on by ischaemia. Even in cases when there are coronary collaterals present, the majority of patients who have a CTO still have some degree of LV dysfunction. PCI to CTO lesions is a technically complex treatment that is performed in the hope of a functional recovery, which has been found to enhance the possibility of survival. Objective To investigate the impact of CTO revascularization on LV function using LV GLS. Methods This study is a prospective observational study that was conducted at Ain Shams university hospitals, in the time interval from October 2022 till October 2023. The study included 30 consecutive patients with CTO lesions who underwent successful PCI. All the patient underwent assessment of GLS of LV before PCI and two months after. Results There was a significant improvement in GLS in the follow up study; P value was