Intraurethral Steroid Injection Following Visual Internal Uerthrotomy in the Management of Anterior Urethral Strictures

Abstract Background Urethral strictures can occur due to trauma, infection, ischemia, inflammation, or unknown causes. As a result, scar tissue forms in the epithelium, which leads to decrease in caliber of the urethral lumen. Objective to evaluate the effect of local intraurethral injection of steroid in treatment of urethral stricture after visual urethrotomy. Patients and Methods Our study was done at the Ain Shams University Hospitals and the Urology department of National institute of Nephrology and Urology. Thirty male Patients with anterior urethral strictures were divided into two groups: Group A (IU only) and Group B (IU+ corticosteroids). Results Our study revealed that internal urethrotomy for anterior urethral stricture with intrauretheral injection of 40 mg methyl prednisone acetate decrease the recurrence rate of the urethral stricture. Conclusion Intraurethral corticosteroids injections at stricture site follows VIU seems to be an effective modality of treatment in decreasing the incidence of recurrent stricture after VIU. However more studies with larger population and long interval follow up are required for better evaluation.