Aluminium mobilization following renal allograft transplantation may have an immunomodulatory role by reducing the incidence of graft rejection

Aluminium mobilization following renal allograft transplantation may have an immunomodulatory role by reducing the incidence of graft rejection

Urinary aluminium excretion was prospectively monitored during the first year following first cadaver renal allograft transplantation in 79 consecutive patients. Plasma and urinary aluminium concentrations steadily declined with time. Thirty-five patients had 0–1 episodes of acute graft rejection co...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 1993, Vol.8 (3), p.244-249
Hauptverfasser: Davenport, A., Davison, A. M., Newton, K. E., Toothill, C., Will, E. J.
Format: Artikel
Sprache:eng
Schlagworte:
acute rejection
Adolescent
Adult
Aged
aluminium
Aluminum - blood
Aluminum - metabolism
Aluminum - urine
Body Burden
Female
Graft Rejection
Humans
Kidney Transplantation - immunology
Male
Middle Aged
Prospective Studies
renal transplant
Transplantation, Homologous
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Zusammenfassung:Urinary aluminium excretion was prospectively monitored during the first year following first cadaver renal allograft transplantation in 79 consecutive patients. Plasma and urinary aluminium concentrations steadily declined with time. Thirty-five patients had 0–1 episodes of acute graft rejection compared to 44 with two or more rejections; more of the former group had been prescribed aluminium-containing phosphate binders (74% versus 56%, P
ISSN:0931-0509
1460-2385
1460-2385
DOI:10.1093/oxfordjournals.ndt.a092440