Pulmonary Artery Aneurysm in Behcet’s Disease Manifesting as Haemoptysis: A Case Report and Literature Review

Abstract Pulmonary artery aneurysm (PAA) in Behcet’s disease is a rare yet potentially life-threatening manifestation, often presenting as haemoptysis. We present a case report of a 33-year-old male with recurrent haemoptysis and a history of oral and genital ulcers, diagnosed with Behcet’s disease complicated by PAA. Diagnostic workup, including imaging and laboratory tests, confirmed the diagnosis, leading to prompt initiation of immunosuppressive therapy and meticulous follow-up. The patient showed significant clinical improvement with reduced ulcer severity and no new episodes of haemoptysis during one-year follow-up. Our case underscores the importance of early recognition, multidisciplinary management, and close monitoring to optimize outcomes in Behcet’s disease with pulmonary involvement. A comprehensive literature review further elucidates the clinical nuances, diagnostic challenges, and therapeutic strategies associated with this rare manifestation, highlighting the need for collaborative care and tailored interventions to mitigate complications and improve patient prognosis. Key clinical message Behcet’s disease can present with pulmonary artery aneurysm, necessitating vigilant monitoring and prompt intervention to prevent severe complications like haemoptysis. Multidisciplinary collaboration is vital for tailored management and improved patient outcomes.