Rhinovirus Detection in Children Hospitalized with Acute Respiratory Illness and Asymptomatic Outpatients

Abstract Background Rhinoviruses (HRV) are a leading cause of acute respiratory illness (ARI) in children. Clinical manifestations include asymptomatic, upper, and lower respiratory disease. The objective of this study was to compare symptomatic and asymptomatic HRV detection, as well as symptomatology associated with HRV genotypes (HRV-A, HRV-B, and HRV-C). Methods Six New Vaccine Surveillance Network sites performed prospective ARI surveillance from 11/1/2015–6/30/2016 and enrolled hospitalized children