Paving the road for biomedicine: genome editing and stem cells in primates

Non-human primates (NHPs) are similar with humans in their anatomy, physiology, genetics and neural functions, and in their cognition, emotions and social behavior. "Ihe NHP model has played an important role in the biomedical research, development of vaccines and drugs and new therapies for many di...

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Veröffentlicht in:National science review 2017-07, Vol.4 (4), p.543-549
Hauptverfasser: Niu, Yuyu, Li, Tianqing, Ji, Weizhi
Format: Artikel
Sprache:eng
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Zusammenfassung:Non-human primates (NHPs) are similar with humans in their anatomy, physiology, genetics and neural functions, and in their cognition, emotions and social behavior. "Ihe NHP model has played an important role in the biomedical research, development of vaccines and drugs and new therapies for many diseases. Recent advances in genome editing have generated NHP models for human diseases. Genome editing integrated with derivation ofNHP pluripotent stem ceils now provides an optimal resource to regenerate medicine.
ISSN:2095-5138
2053-714X
DOI:10.1093/nsr/nwx094