4482 PREGNANCY AND RENAL OUTCOMES IN WOMEN WITH CHRONIC KIDNEY DISEASE: A POPULATION STUDY

Abstract Background and Aims Women with CKD stages 3-5 are at higher risk of adverse pregnancy outcomes, including preterm delivery and low birthweight and progression of kidney disease. However, data describing outcomes of women with less severe kidney disease are limited, and few compare with women normal renal function. Furthermore, most studies report cohorts recruited from specialist clinics and may not be representative. This study aimed to describe pregnancy outcomes in a UK population cohort according to pre-conception eGFR 90 eGFR > 90 ml/min/1.73 m2 with proteinuria eGFR 60-89 ml/min/1.73 m2 eGFR ≤59 ml/min/1.73 m2) (N = 12852) (N = 221) (N = 1170) (N = 14) Age at conception (mean (SD)) 27.5 (5.5) 27.7 (5.9) 30.8 (5.4) 28.4 (6.4) Live birth (%) 10,226 (99.5) 208 (99.5) 956 (99.7) 11 (100.0) Gestation at delivery (days) (median [IQR]) 278 [271, 284] 274 [265, 281] 277 [271, 284] 278 [270.5, 283] Birthweight (mean (SD)) 3385 (706) 3355 (653) 3368 (615) 3073 (663) Preterm birth