MO924: Association Between Dynapenia, Cardiovascular Hospitalizations and All-Cause Mortality Among Patients on Hemodialysis

Abstract BACKGROUND AND AIMS Low muscle strength is associated with adverse clinical outcomes in patients on hemodialysis (HD). However, the association between dynapenia, characterized by both low handgrip strength (HGS) and leg strength (LS) and long-term clinical outcomes in patients on HD has not yet been reported. Therefore, this study investigated whether dynapenia was associated with higher cardiovascular (CV) hospitalization risk and all-cause mortality in patients on HD. METHOD This retrospective study used the data of outpatients on HD from two dialysis facilities between October 2002 and March 2020. This study was approved by the Institutional Review Board/Ethics Committee of Kitasato University of Allied Health Sciences and was conducted in accordance with the principles of the Declaration of Helsinki. All participants provided written informed consent before inclusion in the study. Low muscle strength was defined as an HGS of