MO754: Impact of Calcium-to-Magnesium Ratio on Carotid Intima-Media Thickness—Cardiovascular Risk Assessment in Haemodialysis
Abstract BACKGROUND AND AIMS Cardiovascular disease (CVD) is the leading cause of death in chronic kidney disease patients. The interaction between calcium and magnesium has been associated with several pathophysiological processes that occur in the vessel wall, such as endothelial dysfunction and v...
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Veröffentlicht in: | Nephrology, dialysis, transplantation dialysis, transplantation, 2022-05, Vol.37 (Supplement_3) |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Abstract
BACKGROUND AND AIMS
Cardiovascular disease (CVD) is the leading cause of death in chronic kidney disease patients. The interaction between calcium and magnesium has been associated with several pathophysiological processes that occur in the vessel wall, such as endothelial dysfunction and vascular calcification. The aim of this study was to assess the relationship between calcium-to-magnesium (Ca: Mg) ratio and carotid intima-media thickness (CIMT), a widely used risk marker for CVD in the assessment of subclinical atherosclerosis. This study also aimed to establish the role of the Ca: Mg ratio as a predictor of cardiovascular mortality in haemodialysis (HD).
METHOD
Prevalent HD patients were enrolled in the longitudinal prospective study in a single tertiary centre. According to CIMT measured through B-mode ultrasound, the patients were divided into two groups: ≥0.9 mm (G1) and |
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ISSN: | 0931-0509 1460-2385 |
DOI: | 10.1093/ndt/gfac079.033 |