MO167: SAFETY OF SGLT2 INHIBITORS (SGLT2I) IN PEOPLE OVER 75 YEARS

Abstract BACKGROUND AND AIMS The use of iSGLT2 in people over 75 years was initially associated with a higher rate of adverse effects (AEs). Subsequent clinical trials have consistently demonstrated no increase of serious adverse effects in this group of patients, but the incidence of minor adverse...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2022-05, Vol.37 (Supplement_3)
Hauptverfasser: Vidas, Maria Marques, Domenech, Ester, Testillano, Lucía Martin, Maroto, Alba, Lopez, Paula, Portoles, Jose' M
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract BACKGROUND AND AIMS The use of iSGLT2 in people over 75 years was initially associated with a higher rate of adverse effects (AEs). Subsequent clinical trials have consistently demonstrated no increase of serious adverse effects in this group of patients, but the incidence of minor adverse events remains to be analysed in this group of patients The objective of this study is to evaluate in real life the incidence of adverse effects attributable to this family of drugs in patients aged 75 years (75+) or more at the beginning of treatment with iSGLT2 taking as reference population patients aged less than 75 years (
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfac066.069