RNA recognition and recognition control of α-peptide ribonucleic acids containing arginine residue by external factors

A novel nucleic acid model using α-peptide ribonucleic acid (α-PRNA) possessing alternative α-PRNA/lysine and α-PRNA/arginine sequences, where the lysine or arginine residue are expected to stabilize the complex not only by the conventional hydrogen-bonding interactions between the complementary nucleobase pairs but also through the electrostatic interactions between basic amino acid side-chain groups and DNA's phosphate anions on the backbone. These α-PRNAs form stable sequence-specific complex with the complementary DNA.