Structural stability and length of I-motif of G-quartet in DNA octaplex

Structural stability and length of I-motif of G-quartet in DNA octaplex

To confirm that longer DNA strands with sequences gcGA[G]nAgc can from an octaplex, X-ray analyses at n>l have been performed. Several crystals of d(gcGA[G]2Agc) are obtained under different conditions. It has been found that the crystal obtained with cobalt hexamine suggests a hexaplex formation...

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Veröffentlicht in:Nucleic Acids Symposium Series 2004-11, Vol.48 (1), p.121-122
Hauptverfasser: Mitomi, Kenta, Ciengshin, Tanashaya, Kondo, Jiro, Takénaka, Akio
Format: Artikel
Sprache:eng
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Zusammenfassung:To confirm that longer DNA strands with sequences gcGA[G]nAgc can from an octaplex, X-ray analyses at n>l have been performed. Several crystals of d(gcGA[G]2Agc) are obtained under different conditions. It has been found that the crystal obtained with cobalt hexamine suggests a hexaplex formation, while the crystal obtained with Mg2+ and Na+ ions suggests an octaplex formation.
ISSN:0261-3166
1746-8272
DOI:10.1093/nass/48.1.121