Poly(U, s4U) as a synthetic messenger RNA for polyphenylalanine synthesis in a cell-free system derived from rat liver

Poly(U, s4U) as a synthetic messenger RNA for polyphenylalanine synthesis in a cell-free system derived from rat liver

Two different U and s4U containing polymers with U:s4U ratio of 3:1 and 5:1 were synthesized. Their activity as messenger RNA was studied in an amino acid incorporation cell-free system from rat liver. It was shown that both copolymers can stimulate the incorporation of phenylalanine into oligopheny...

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Veröffentlicht in:Nucleic acids research 1975-04, Vol.2 (4), p.595-601
Hauptverfasser: Keren-Zur, M., Hochberg, A.A., de Groot, N., Lapidot, Y.
Format: Artikel
Sprache:eng
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Zusammenfassung:Two different U and s4U containing polymers with U:s4U ratio of 3:1 and 5:1 were synthesized. Their activity as messenger RNA was studied in an amino acid incorporation cell-free system from rat liver. It was shown that both copolymers can stimulate the incorporation of phenylalanine into oligophenylalanyl-tRNA.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/2.4.595