Low S-adenosylmethionine/ S-adenosylhomocysteine Ratio in Urine is Associated with Chronic Kidney Disease

Abstract Objective To evaluate the association of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in urine with chronic kidney disease (CKD). Methods Case-control study including 50 patients with CKD and 20 healthy volunteers. Results SAM level and SAM/SAH ratio in urine were significant...

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Veröffentlicht in:	Laboratory medicine 2020-01, Vol.51 (1), p.80-85
Hauptverfasser:	Kruglova, Maria Petrovna, Grachev, Sergej Vital’evich, Bulgakova, Polina Olegovna, Ivanov, Alexander Vladimirovich, Virus, Edward Danielevich, Nikiforova, Ksenya Alexandrovna, Fedoseev, Anatolij Nikolaevich, Savina, Galina Dmitrievna, Kubatiev, Aslan Amirkhanovich
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic kidney failure Homocysteine Kidney diseases Life Sciences & Biomedicine Medical Laboratory Technology Medical research Medicine, Experimental S-adenosylmethionine Science & Technology Type 2 diabetes Urine
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Beschreibung
Zusammenfassung:	Abstract Objective To evaluate the association of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in urine with chronic kidney disease (CKD). Methods Case-control study including 50 patients with CKD and 20 healthy volunteers. Results SAM level and SAM/SAH ratio in urine were significantly lower in patients than in control individuals (P
ISSN:	0007-5027 1943-7730
DOI:	10.1093/labmed/lmz035