Dietary Composition and Tissue Protein Synthesis

Skin collagen synthesis as measured by the uptake of radioglycine was considerably decreased in rats fed amino acid-deficient diets. Excess dietary tryptophan (1.5% added to a 12% casein diet) had a similar although less marked effect. The composition of skin with respect to its water, fat, collagen...

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Veröffentlicht in:The Journal of nutrition 1962-10, Vol.78 (2), p.133-138
Hauptverfasser: Nimni, M.E., Hom, D., Bavetta, L.A.
Format: Artikel
Sprache:eng
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Zusammenfassung:Skin collagen synthesis as measured by the uptake of radioglycine was considerably decreased in rats fed amino acid-deficient diets. Excess dietary tryptophan (1.5% added to a 12% casein diet) had a similar although less marked effect. The composition of skin with respect to its water, fat, collagen and fat-free total solids was shown to be greatly dependent upon the nature of the diet. The total amount of collagen synthesized as a response to the subcutaneous implantation of polyvinyl sponges was slightly decreased by the consumption of diets inadequate for optimal growth. Serum glutamic-oxaloacetic transaminase was increased in the animals fed amino acid-deficient diets, whereas liver arginase activity seemed to reflect the quantity of protein ingested rather than its amino acid composition.
ISSN:0022-3166
DOI:10.1093/jn/78.2.133