401 Markers of Smoke Inhalation Injury in Adult Burned Patients

Abstract Introduction Inhalation injury continues to represent a major source of morbidity and mortality in burned patients. The aim of the present study is to examine potential markers of smoke inhalation injury in adult burned patients classified with either mild, moderate, severe, or no inhalation injury within one year after injury. Methods Inhalation injury was classified into one of four groups in adult burned patients (n=21, 20 ± 19% total body surface area burn, ages 47 ± 15 years), and plasma was collected from each subject. An amino acid panel, along with concentrations of asymmetric (ADMA) and symmetric dimethylarginine (SDMA), was analyzed for each sample. Significance was accepted at p