The Effect of Cortisone and Somatotrophic Hormone on Vaccinia Virus Lesions and Benzyl Alcohol Toxicity in the Embryonated Egg

Embryonated eggs infected with vaccinia on the chorioallantic membrane and treated with cortisone showed a reduced mortality rate, but no significant change in number and size of lesions, as compared to infected eggs treated with the aqueous vehicle of cortisone containing benzyl alcohol. The concomitant use of cortisone and somatotrophic hormone reversed this protective effect of cortisone, but it significantly reduced the number and size of lesions as compared to eggs infected but untreated or those infected and treated solely with cortisone, somatotrophic hormone, or aqueous vehicle of cortisone.