Primary Drug-Resistant Mycobacterium tuberculosis Isolated in Massachusetts in 1972
Among the 731 persons with Mycobacterium tuberculosis infection who were tested in Massachusetts in 1972, an incidence of 3.16% (23 cases) of primary resistance to antituberculous drugs was observed. Nine cases (1.23 %) were resistant to isoniazid alone, and six cases (0.82%) were resistant to three...
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Veröffentlicht in: | The Journal of infectious diseases 1974-09, Vol.130 (3), p.293-294 |
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Sprache: | eng |
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Zusammenfassung: | Among the 731 persons with Mycobacterium tuberculosis infection who were tested in Massachusetts in 1972, an incidence of 3.16% (23 cases) of primary resistance to antituberculous drugs was observed. Nine cases (1.23 %) were resistant to isoniazid alone, and six cases (0.82%) were resistant to three drugs (isoniazid, streptomycin, and either para-aminosalicylic acid or ethambutol). Four cases (0.55%) were resistant to streptomycin and para-aminosalicylic acid combined, and one case (0.14%) was resistant to each of the following: streptomycin alone, isoniazid and streptomycin, isoniazid and para-aminosalicylic acid, and isoniazid and ethambutol. Twelve of the 23 primary drug-resistant patients had a history of alcoholism or addiction to narcotics; 10 of the 12 addicts were infected by multiple drug-resistant tubercle bacilli. |
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ISSN: | 0022-1899 1537-6613 |
DOI: | 10.1093/infdis/130.3.293 |