P-050 Reproductive results in vasectomized patients according to the time of the surgical procedure

Abstract Study question Is there a difference in reproductive outcomes in vasectomized patients related to the time of the surgical procedure undergoing ART? Summary answer The time-interval post-vascetomy sperm recovery not affected until 19 years after procedure, although p 20 years procedure What is known already Assisted reproductive techniques (ART) have helped vasectomized men who want to have children again, situations that are currently seen relatively frequently. However, an adequate period of time from surgery to initiate ART has not been established. For this reason, it is intended to retrospectively analyze the reproductive results with ICSI, in couples where the man has undergone a previous vasectomy, relating them to the time elapsed since the surgical procedure. Study design, size, duration Retrospective study from 2000 to 2019 of ICSI cycles with 200 patients with their own oocytes, 38 patients with donated oocytes, carried out at IVI Alicante and Murcia. The groups were distributed according to the time elapsed since the man was vasectomized and the treatment carried out: Group A ( 20 years) discriminated as follows: Own/donated oocytes: group A: 90/26, B: 70/9 and C: 40/3. Participants/materials, setting, methods Inclusion criteria: A total of 239 patients and their partners who undergo the intracytoplasmic sperm injection technique with their own and donated oocytes, before Testicular Sperm Extraction (TESE) surgery and freezing-thamwing a biopsy of testicular tissue after. The statistical analysis was carried out with the statistical software R, version 4.0, linear and multiple regression, establishing significant differences when p